Be the first to like.

Share

Fentanyl, a powerful synthetic opioid, poses an increasing public health threat. Low production costs encourage suppliers to “cut” heroin with the drug, particularly white powder heroin sold in the eastern United States.1Fentanyl also appears as a prevalent active ingredient in counterfeit OxyContin (oxycodone) tablets. The result is that fentanyl plays a major role in rising mortality due to heroin or opioid overdose. It poses a serious overdose risk because it can rapidly suppress respiration and cause death more quickly than do other opioids.

From 2012 through 2014, the number of reported deaths involving fentanyl more than doubled, from 2628 to 5544. We estimate that 41% of the roughly 7100 heroin-related deaths during this period involved fentanyl.2 The graphDrug-Overdose Deaths Involving Opioids, by Type of Opioid, United States, 2000–2014. illustrates this calculation, placing heroin and fentanyl at the center of continued growth in opioid-related mortality.

Governments are struggling to determine how best to deploy the tools at their disposal to address widespread fentanyl-related deaths. We believe there is merit to a harm-reduction approach involving increased transparency for users and public health and public safety organizations, harm-reduction policing, expanded naloxone use, and targeted treatment.

… Read More

Be the first to like.

Share
NEJM

Tags: , , , , , , ,

Leave a Reply