David Dobbs writes, “An early halt to a trial of deep brain stimulation for depression reveals little about the treatment but more about the changing nature of clinical trials.”

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David Gerber writes, “I couldn’t think of a single way in which the patient’s prior experience with cancer would interfere with treatments or assessments on a lung cancer trial. And yet I couldn’t enroll him…. Unfortunately, many sick patients are being denied the opportunity to test new drugs that might save their lives. It’s time for this to change.”

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President Donald Trump’s likely pick to lead the Centers for Disease Control and Prevention is facing significant criticism because of a 20-year-old controversy over shoddy HIV research

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Clinical trial will compare three antiretroviral drug regimens. It will provide data on the use of these newer drugs during pregnancy, helping to ensure that women living with HIV and their infants receive the best available treatments

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Holly Fernandez Lynch writes, “Nevertheless, even the upswing still leaves quite a bit of the glass empty: Results from more than 1 in 4 trials have still not been properly reported. The ethical consequences are substantial, and the government should be using its considerable enforcement authority to put an end to it. But it isn’t.”

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The human immune system can hinder the gene-editing tool, though there could be ways around it

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Earlier this year, when Emily Chodos was about 25 weeks into her pregnancy, she woke up one night feeling horrible. “My hands were tremoring, my heart racing, ” recalls Chodos, who lives near New Haven, Conn. She couldn’t take a deep breath. “I’d never felt so out of control of my body.”

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And sees firsthand how hard it is. Galvanized by his teenage son’s epilepsy diagnosis, Mayes started a new company to try to shepherd a promising inhaler technology for epilepsy through a key clinical trial

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