Nancy Goodman wanted to spend as much time as possible with her dying child. But even as ten-year-old Jacob’s brain cancer worsened, Goodman spent months contacting pharmaceutical companies that were developing drugs that might help him.
‘Compassionate-use’ laws in the United States allow pharmaceutical companies to provide unapproved drugs to patients in desperate need, but many firms provide little or no information on how to request these treatments. They are often reluctant to supply drugs in response to such pleas, especially if drug stocks are limited, although media campaigns on behalf of individual patients can sometimes embarrass firms into providing unapproved treatments. Anecdotes suggest that money and connections are also influential.
Now, ethicists and medical experts are testing what they hope is a fairer system to distribute drugs in short supply. The approach, presented on 6 June at the American Society of Clinical Oncology meeting in Chicago, Illinois, is inspired by the method used to prioritize organ transplants. In a test case, researchers worked with Janssen Pharmaceuticals to determine how to distribute limited supplies of daratumumab, an experimental drug intended to treat multiple myeloma.
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Image: By Tom Varco – Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=1031875
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