New research is zeroing in on a biochemical basis for the placebo effect — possibly opening a Pandora’s box for Western medicine

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The manufacture and distribution of medicines is a global industry, tainted by fake and substandard products. Not only might these drugs not work as expected, but some are even contributing to antimicrobial resistance. So, what’s in your medicine cabinet?

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Five years ago, the phrase “right to try” wasn’t yet an inkling in the minds of its staunchest advocates. Today, the pithy shorthand for the campaign to get dying patients access to experimental treatments has been slapped on bumper stickers, emblazoned on T-shirts, and uttered by some of the most powerful figures in Washington

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“Strict”, “scrupulous” and “rigid”. These are some of the words that have been used to describe the regulation of physician-assisted suicide (PAS) in the Netherlands. But how closely are doctors actually monitored?

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Total costs of Kymriah and the 21 similar drugs in development — known as CAR T-cell therapies — will be far higher than many have imagined, reaching $1 million or more per patient, according to leading cancer experts. The next CAR T-cell drug could be approved as soon as November.

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Back in the 1960s, a woman doctor in Japan created a powerful drug to help mothers who hemorrhage after childbirth. The medicine is inexpensive to make. Safe to use. And stops bleeding quickly by helping keep naturally forming blood clots intact

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Ana Santos Rutschman: “As an FDA scholar at the Jaharis Health Law Institute at DePaul, I worry that faster regulatory review and approval might come at a cost. We may sacrifice safety and efficacy of drugs and devices approved under this new system”

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Academics vet the work of their peers — for free, in their spare time — in a process that is supposed to weed out junk science before it’s published. But researchers say the task is thankless, that it slows down the publication process. To make matters worse, this cornerstone of the scientific method has surprisingly little evidence for its effectiveness, and many mysteries about how it works

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