A one-off injection could one day lower your cholesterol levels for the rest of your life. People born with natural mutations that disable a specific gene have a lower risk of heart disease, with no apparent side effects. Now a single injection has successfully disabled this same gene in animal tests for the first time

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The death rate from heart disease, long in decline, edged up slightly. Death rates — measured as the number of deaths per 100,000 people — have been declining for years, an effect of improvements in health, disease management and medical technology

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