For the first time in human existence, it became practical to change genes throughout the entire human genome with high precision and accuracy. And today, a decade after the introduction of CRISPR, it’s newly apparent that such manipulations have been made to human embryos — a feat achieved by scientists at the Salk Institute in La Jolla and elsewhere

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If there was one misstep that doomed the long and bitter fight by the University of California to wrest key CRISPR patents from the Broad Institute, it was star UC Berkeley scientist Jennifer Doudna’s habit of being scientifically cautious, realistic, and averse to overpromising.

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Jennifer Doudna, a pioneer of the revolutionary genome-editing technology, reflects on how 2015 became the most intense year of her career — and what she’s learnt

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Our Jeffrey Kahn joined other expert witnesses for a hearing of the subcommittee on research and technology to discuss the science and ethics of the use of human gene-editing technologies

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