Victoria Toline would hunch over the kitchen table, steady her hands and draw a bead of liquid from a vial with a small dropper. It was a delicate operation that had become a daily routine — extracting ever tinier doses of the antidepressant she had taken for three years, on and off, and was desperately trying to quit

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Ayelet Waldman, a novelist and former federal public defender, recalled the sunny spring morning she rolled out of bed in her Berkeley, Calif., home and experienced the most curious sensation: She felt alive

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A new study links a dark outlook with greater risk of death from heart disease. But being grumpy might help you in old age

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Since its public launch 10 years ago, Twitter has been used as a social networking platform among friends, an instant messaging service for smartphone users and a promotional tool for corporations and politicians. But it’s also been an invaluable source of data for researchers and scientists – like myself – who want to study how humans feel and function within complex social systems

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At any given moment, you have somewhere between 10 trillion and 100 trillion microorganisms inhabiting your gut — that’s more microbes in your bowels than there are cells in your body. If that isn’t impressive enough, consider that collectively these microbes have about 150 times as many genes as your own genome

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If it works, it’s likely to be expensive, have serious side effects, and help only a subset of patients. But it could also open the door to a whole new field of drug development for other psychiatric conditions, including bipolar disorder, anxiety disorders, and schizophrenia, all of which might be propelled, at least in part, by excess immune activity in the brain

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Go ahead and sulk. Unhappiness won’t kill you. A study published on Wednesday in The Lancet, following one million middle-aged women in Britain for 10 years, finds that the widely held view that happiness enhances health and longevity is unfounded

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Jaime Lowe: My 20-year struggle with bipolar disorder

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