It has been recently reported that a 32 year old Greek woman is 27 weeks pregnant with a child who was conceived after a mitochondrial replacement technique (MRT) – in this case Maternal Spindle Transfer (MST). If true, this would be just the third birth following a reproductive technique that mixes the DNA of three people

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It seems impossible, right? We have been taught from the time we were young that babies are made when a sperm and an egg come together, and the DNA from these two cells combine to make a unique individual with half the DNA from the mother and half from the father. So how can there be a third person involved in this process?

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Two women with gene mutation that causes degenerative disorder will undergo mitochondrial replacement therapy (MRT)

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But the child’s parents have decided to forego long-term monitoring by researchers

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A baby has been born to a previously infertile couple in Ukraine using a new type of “three-person IVF”

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Three Parents

November 7, 2016

Why are bioethicists thinking about the recent birth of a three parent child? Elizabeth Tracey speaks with our Jeffrey Kahn

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ohn Zhang, MD, medical director and founder of New Hope Fertility in New York City, led a team that performed a new technique called spindle nuclear transfer. This technique is a form of mitochondrial manipulation technology that involves removing the nucleus from the mother’s oocyte and transferring it to an enucleated donor oocyte that is then fertilized with the father’s sperm

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