The operation is a daring one: To replace a failing heart valve, cardiologists insert a replacement through a patient’s groin and thread it all the way to the heart, maneuvering it into the site of the old valve

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Gene-edited ‘surrogate sires’ could help spread desirable traits rapidly in some livestock

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Deaths from opioid overdoses have increased dramatically over the last decade. In 2017, the latest year for which the U.S. government has statistics on the trend, more than 47,000 Americans died of opioid overdoses

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Peace Over Promise

March 12, 2019

ALS patient quits taking drug aimed at slowing disease. David Frei, 54, has been struggling with time. Some things he wants to slow down, others he wants to speed up. He can’t keep up with trying to adapt to the paralysis that started in his legs and is creeping up his body. Every solution is temporary

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Will it be useful? As more people get genetic testing to assess their risk of getting cancers and other serious conditions, diabetes has been almost entirely left out — largely because of the difficulty of developing a useful test

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Anne Drapkin Lyerly, a bioethicist and obstetrician, said that there is a deep-seated norm to leave pregnant women out of clinical trials, reinforced by policies that have classified them as “vulnerable” and institutional rules that have made it easier to avoid considering the ­potential risks and benefits altogether

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Artificial intelligence systems are powerful tools for businesses and governments to process data and respond to changing situations, whether on the stock market or on a battlefield. But there are still some things AI isn’t ready for

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Little Falls, Minnesota, didn’t do anything revolutionary. They just made a real effort — and spent real money — treating addiction as a disease, not a crime. With comments from our Brendan Saloner

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