“A lot of women don’t understand just how poor the evidence base is,” said Carleigh Krubiner, PhD, a research scholar at the Johns Hopkins Berman Institute of Ethics. “It really is shocking when you think about how poorly the research enterprise has done.”

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The exclusion of pregnant and lactating women from an effort to vaccinate people exposed to the Ebola virus in the current outbreak is wrong, indefensible, and should be reversed, three Johns Hopkins public health experts wrote Monday in an opinion article published in STAT.

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Clinical trial will compare three antiretroviral drug regimens. It will provide data on the use of these newer drugs during pregnancy, helping to ensure that women living with HIV and their infants receive the best available treatments

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A federal task force is now trying to help

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Ethics guidance on priorities, inclusion, and evidence generation – enriched with additional links and resources, and broken into expandable sections for ease of reading and reference

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Earlier this year, when Emily Chodos was about 25 weeks into her pregnancy, she woke up one night feeling horrible. “My hands were tremoring, my heart racing, ” recalls Chodos, who lives near New Haven, Conn. She couldn’t take a deep breath. “I’d never felt so out of control of my body.”

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Some vaccine developers are taking steps to include them, in line with bioethicists’ urging, but it will likely take years before any expectant mothers are enrolled

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Pregnancy Paradox

August 14, 2017

The dangers of not testing drugs on pregnant women. Pregnant women can get sick. And women with illnesses do get pregnant. Yet most drugs have never been tested for their effects during pregnancy

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